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240722s2024 xx |||||o 00| ||eng c |
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|a 10.1002/adma.202405892
|2 doi
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|a pubmed24n1478.xml
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|a (NLM)39036824
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|a DE-627
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|e rakwb
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|a eng
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|a Zhu, Ziyi
|e verfasserin
|4 aut
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|a Tissue/Organ Adaptable Bioelectronic Silk-Based Implants
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|c 2024
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Revised 22.07.2024
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|a published: Print-Electronic
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|a Citation Status Publisher
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|a © 2024 Wiley‐VCH GmbH.
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|a Implantable bioelectronic devices, designed for both monitoring and modulating living organisms, require functional and biological adaptability. Pure silk is innovatively employed, which is known for its excellent biocompatibility, to engineer water-triggered, geometrically reconfigurable membranes, on which functions can be integrated by Micro Electro Mechanical System (MEMS) techniques and specially functionalized silk. These devices can undergo programmed shape deformations within 10 min once triggered by water, and thus establishing stable bioelectronic interfaces with natively fitted geometries. As a testament to the applicability of this approach, a twining peripheral nerve electrode is designed, fabricated, and rigorously tested, demonstrating its efficacy in nerve modulation while ensuring biocompatibility for successful implantation
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|a Journal Article
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|a bioelectronic implant
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|a nerve modulation
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|a silk material
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|a supercontraction
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|a tissue/organ adaptable
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|a Yan, Zhiwen
|e verfasserin
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|a Ni, Siyuan
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|a Yang, Huiran
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|a Xie, Yating
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|a Wang, Xueying
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|a Zou, Dujuan
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|a Tao, Chen
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|a Jiang, Wanqi
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|a Jiang, Jianbo
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|a Su, Zexi
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|a Xia, Yuxin
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|a Zhou, Zhitao
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|a Sun, Liuyang
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|a Fan, Cunyi
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|a Tao, Tiger H
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|a Wei, Xiaoling
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|a Qian, Yun
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|a Liu, Keyin
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|4 aut
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| 773 |
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
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|g (2024) vom: 22. Juli, Seite e2405892
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|g year:2024
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|u http://dx.doi.org/10.1002/adma.202405892
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