Tissue/Organ Adaptable Bioelectronic Silk-Based Implants
© 2024 Wiley‐VCH GmbH.
Publié dans: | Advanced materials (Deerfield Beach, Fla.). - 1998. - 36(2024), 38 vom: 15. Sept., Seite e2405892 |
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Auteur principal: | |
Autres auteurs: | , , , , , , , , , , , , , , , , , |
Format: | Article en ligne |
Langue: | English |
Publié: |
2024
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Accès à la collection: | Advanced materials (Deerfield Beach, Fla.) |
Sujets: | Journal Article bioelectronic implant nerve modulation silk material supercontraction tissue/organ adaptable Silk Biocompatible Materials |
Résumé: | © 2024 Wiley‐VCH GmbH. Implantable bioelectronic devices, designed for both monitoring and modulating living organisms, require functional and biological adaptability. Pure silk is innovatively employed, which is known for its excellent biocompatibility, to engineer water-triggered, geometrically reconfigurable membranes, on which functions can be integrated by Micro Electro Mechanical System (MEMS) techniques and specially functionalized silk. These devices can undergo programmed shape deformations within 10 min once triggered by water, and thus establishing stable bioelectronic interfaces with natively fitted geometries. As a testament to the applicability of this approach, a twining peripheral nerve electrode is designed, fabricated, and rigorously tested, demonstrating its efficacy in nerve modulation while ensuring biocompatibility for successful implantation |
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Description: | Date Completed 03.10.2024 Date Revised 03.10.2024 published: Print-Electronic Citation Status MEDLINE |
ISSN: | 1521-4095 |
DOI: | 10.1002/adma.202405892 |