Investigating the effects of non-steroidal anti-inflammatory drugs (NSAIDs) on the composition and ultrastructure of green leafy vegetables with important nutritional values
Copyright © 2020 Elsevier Masson SAS. All rights reserved.
| Veröffentlicht in: | Plant physiology and biochemistry : PPB. - 1991. - 151(2020) vom: 15. Juni, Seite 342-351 |
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| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2020
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| Zugriff auf das übergeordnete Werk: | Plant physiology and biochemistry : PPB |
| Schlagworte: | Journal Article Abiotic stress Carotenoids Chlorophylls Green leafy vegetables Polyphenols Ultrastructure Anti-Inflammatory Agents, Non-Steroidal Environmental Pollutants |
| Zusammenfassung: | Copyright © 2020 Elsevier Masson SAS. All rights reserved. The global presence of pharmaceuticals in the environment has been particularly considered a concerning problem with unknown consequences. Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most frequently prescribed drugs in the world, and as a result, they are commonly found in different environmental compartments. In the present work, we studied the effects of NSAIDs (diclofenac, ibuprofen, and naproxen) on the composition and ultrastructure of Atriplex patula L., S. oleracea, and Lactuca sativa L., three green leafy vegetables with significant nutritional value. Contaminant solutions of NSAIDs were applied every two days using concentrations of 0.1 mg L-1, 0.5 mg L-1, and 1 mg L-1. After eight weeks of exposure of the green leafy vegetables to the selected NSAIDs, the chlorophylls (a + b), carotenoids (zeaxanthin, lutein, and ß-carotene), total polyphenol and total flavonoid contents, antioxidant capacity, and the ultrastructural modifications were determined. The obtained results indicated a moderate reduction in the assimilating pigments, total polyphenol and flavonoid contents. In addition, ultrastructural damages of the chloroplasts and cell walls were observed in the leaves of the selected vegetables, which were exposed to abiotic stress-induced by NSAIDs. All data collectively suggest that this group of drugs induced harmful effects on plants, and implicitly they may also negatively affected human health on the long term |
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| Beschreibung: | Date Completed 19.08.2020 Date Revised 30.09.2020 published: Print-Electronic Citation Status MEDLINE |
| ISSN: | 1873-2690 |
| DOI: | 10.1016/j.plaphy.2020.03.046 |