Neural Image Compression for Gigapixel Histopathology Image Analysis
We propose Neural Image Compression (NIC), a two-step method to build convolutional neural networks for gigapixel image analysis solely using weak image-level labels. First, gigapixel images are compressed using a neural network trained in an unsupervised fashion, retaining high-level information wh...
Veröffentlicht in: | IEEE transactions on pattern analysis and machine intelligence. - 1979. - 43(2021), 2 vom: 01. Feb., Seite 567-578 |
---|---|
1. Verfasser: | |
Weitere Verfasser: | , , |
Format: | Online-Aufsatz |
Sprache: | English |
Veröffentlicht: |
2021
|
Zugriff auf das übergeordnete Werk: | IEEE transactions on pattern analysis and machine intelligence |
Schlagworte: | Journal Article Research Support, Non-U.S. Gov't |
Zusammenfassung: | We propose Neural Image Compression (NIC), a two-step method to build convolutional neural networks for gigapixel image analysis solely using weak image-level labels. First, gigapixel images are compressed using a neural network trained in an unsupervised fashion, retaining high-level information while suppressing pixel-level noise. Second, a convolutional neural network (CNN) is trained on these compressed image representations to predict image-level labels, avoiding the need for fine-grained manual annotations. We compared several encoding strategies, namely reconstruction error minimization, contrastive training and adversarial feature learning, and evaluated NIC on a synthetic task and two public histopathology datasets. We found that NIC can exploit visual cues associated with image-level labels successfully, integrating both global and local visual information. Furthermore, we visualized the regions of the input gigapixel images where the CNN attended to, and confirmed that they overlapped with annotations from human experts |
---|---|
Beschreibung: | Date Completed 10.12.2021 Date Revised 14.12.2021 published: Print-Electronic Citation Status MEDLINE |
ISSN: | 1939-3539 |
DOI: | 10.1109/TPAMI.2019.2936841 |