Alpha-1,3-galactosyltransferase-deficient miniature pigs produced by serial cloning using neonatal skin fibroblasts with loss of heterozygosity

OBJECTIVE: Production of alpha-1,3-galactosyltransferase (αGT)-deficient pigs is essential to overcome xenograft rejection in pig-to-human xenotransplantation. However, the production of such pigs requires a great deal of cost, time, and labor. Heterozygous αGT knockout pigs should be bred at least...

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Veröffentlicht in:Asian-Australasian journal of animal sciences. - 1998. - 30(2017), 3 vom: 20. März, Seite 439-445
1. Verfasser: Kim, Young June (VerfasserIn)
Weitere Verfasser: Ahn, Kwang Sung, Kim, Minjeong, Kim, Min Ju, Ahn, Jin Seop, Ryu, Junghyun, Heo, Soon Young, Park, Sang-Min, Kang, Jee Hyun, Choi, You Jung, Shim, Hosup
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2017
Zugriff auf das übergeordnete Werk:Asian-Australasian journal of animal sciences
Schlagworte:Journal Article 3-galactosyltransferase Alpha-1 Gene Targeting Loss of heterozygosity Nuclear Transfer Pig