Alpha-1,3-galactosyltransferase-deficient miniature pigs produced by serial cloning using neonatal skin fibroblasts with loss of heterozygosity
OBJECTIVE: Production of alpha-1,3-galactosyltransferase (αGT)-deficient pigs is essential to overcome xenograft rejection in pig-to-human xenotransplantation. However, the production of such pigs requires a great deal of cost, time, and labor. Heterozygous αGT knockout pigs should be bred at least...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | Asian-Australasian journal of animal sciences. - 1998. - 30(2017), 3 vom: 20. März, Seite 439-445
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1. Verfasser: |
Kim, Young June
(VerfasserIn) |
Weitere Verfasser: |
Ahn, Kwang Sung,
Kim, Minjeong,
Kim, Min Ju,
Ahn, Jin Seop,
Ryu, Junghyun,
Heo, Soon Young,
Park, Sang-Min,
Kang, Jee Hyun,
Choi, You Jung,
Shim, Hosup |
Format: | Online-Aufsatz
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Sprache: | English |
Veröffentlicht: |
2017
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Zugriff auf das übergeordnete Werk: | Asian-Australasian journal of animal sciences
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Schlagworte: | Journal Article
3-galactosyltransferase
Alpha-1
Gene Targeting
Loss of heterozygosity
Nuclear Transfer
Pig |