Targeted Editing of Myostatin Gene in Sheep by Transcription Activator-like Effector Nucleases

Myostatin (MSTN) is a secreted growth factor expressed in skeletal muscle and adipose tissue that negatively regulates skeletal muscle mass. Gene knockout of MSTN can result in increasing muscle mass in sheep. The objectives were to investigate whether myostatin gene can be edited in sheep by transc...

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Veröffentlicht in:Asian-Australasian journal of animal sciences. - 1998. - 29(2016), 3 vom: 01. März, Seite 413-8
1. Verfasser: Zhao, Xinxia (VerfasserIn)
Weitere Verfasser: Ni, Wei, Chen, Chuangfu, Sai, Wujiafu, Qiao, Jun, Sheng, Jingliang, Zhang, Hui, Li, Guozhong, Wang, Dawei, Hu, Shengwei
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2016
Zugriff auf das übergeordnete Werk:Asian-Australasian journal of animal sciences
Schlagworte:Journal Article Myostatin Sheep Primary Fibroblasts Targeted Gene Editing Transcription Activator-like Effector Nucleases