Targeted Editing of Myostatin Gene in Sheep by Transcription Activator-like Effector Nucleases
Myostatin (MSTN) is a secreted growth factor expressed in skeletal muscle and adipose tissue that negatively regulates skeletal muscle mass. Gene knockout of MSTN can result in increasing muscle mass in sheep. The objectives were to investigate whether myostatin gene can be edited in sheep by transc...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | Asian-Australasian journal of animal sciences. - 1998. - 29(2016), 3 vom: 01. März, Seite 413-8
|
1. Verfasser: |
Zhao, Xinxia
(VerfasserIn) |
Weitere Verfasser: |
Ni, Wei,
Chen, Chuangfu,
Sai, Wujiafu,
Qiao, Jun,
Sheng, Jingliang,
Zhang, Hui,
Li, Guozhong,
Wang, Dawei,
Hu, Shengwei |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2016
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Zugriff auf das übergeordnete Werk: | Asian-Australasian journal of animal sciences
|
Schlagworte: | Journal Article
Myostatin
Sheep Primary Fibroblasts
Targeted Gene Editing
Transcription Activator-like Effector Nucleases |