Reducing the cytotoxity of poly(amidoamine) dendrimers by modification of a single layer of carboxybetaine

The surface primary amines of generation five poly(amido amine) (G5 PAMAM) dendrimer were modified by different amounts of carboxybetaine acrylamide (CBAA). As a result, the fully modified molecules (CBAA-PAMAM-20, obtained from the 20:1 molar ratio of CBAA molecules to amino groups in modification...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 29(2013), 28 vom: 16. Juli, Seite 8914-21
1. Verfasser: Wang, Longgang (VerfasserIn)
Weitere Verfasser: Wang, Zhen, Ma, Guanglong, Lin, Weifeng, Chen, Shengfu
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Biocompatible Materials Dendrimers PAMAM Starburst Proteins Betaine 3SCV180C9W