Stability of proteins inside a hydrophobic cavity

We study the effects of confinement and hydrophobicity of a spherical cavity on the structural and thermal stability of proteins in the framework of a hydrophobic-polar (HP) lattice model. We observe that a neutral confinement stabilizes the folded state of the protein by eliminating many of the ope...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 29(2013), 28 vom: 16. Juli, Seite 8922-8
1. Verfasser: Radhakrishna, Mithun (VerfasserIn)
Weitere Verfasser: Grimaldi, Joseph, Belfort, Georges, Kumar, Sanat K
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2013
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, U.S. Gov't, Non-P.H.S. Methacrylates Proteins SBA-15 methacrylic acid 1CS02G8656 Silicon Dioxide 7631-86-9 Alcohol Dehydrogenase EC 1.1.1.1