Proteomic analysis for the study of amniotic fluid protein composition

Amniotic fluid (AF), routinely used for prenatal diagnosis, contains large amounts of proteins produced by the amnion epithelial cells, fetal tissues, fetal excretions and placental tissuesAlthough many amniotic fluid proteins have been identified and are currently used to detect potential fetal ano...

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Veröffentlicht in:Journal of prenatal medicine. - 2007. - 3(2009), 3 vom: 30. Juli, Seite 39-41
1. Verfasser: Perluigi, Marzia (VerfasserIn)
Weitere Verfasser: Di Domenico, Fabio, Cini, Chiara, Coccia, Raffaella, Giorlandino, Francesca Romana, Giorlandino, Maurizio, Cignini, Pietro, Mesoraca, Alvaro, Giorlandino, Claudio
Format: Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Journal of prenatal medicine
Schlagworte:Journal Article amniotic fluid protein proteomic analysis
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520 |a Amniotic fluid (AF), routinely used for prenatal diagnosis, contains large amounts of proteins produced by the amnion epithelial cells, fetal tissues, fetal excretions and placental tissuesAlthough many amniotic fluid proteins have been identified and are currently used to detect potential fetal anomalies, little is known about the functions of these proteins and how they interact with one another. Identification of changes in the protein content of amniotic fluid, therefore, may be used to detect a particular type of pathology, or to ascertain a specific genetic disorder. In the present work we used a proteomic approach, combining 2DE and MS, in order to study the protein composition of AFS 
650 4 |a Journal Article 
650 4 |a amniotic fluid 
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700 1 |a Di Domenico, Fabio  |e verfasserin  |4 aut 
700 1 |a Cini, Chiara  |e verfasserin  |4 aut 
700 1 |a Coccia, Raffaella  |e verfasserin  |4 aut 
700 1 |a Giorlandino, Francesca Romana  |e verfasserin  |4 aut 
700 1 |a Giorlandino, Maurizio  |e verfasserin  |4 aut 
700 1 |a Cignini, Pietro  |e verfasserin  |4 aut 
700 1 |a Mesoraca, Alvaro  |e verfasserin  |4 aut 
700 1 |a Giorlandino, Claudio  |e verfasserin  |4 aut 
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