Proteomic analysis for the study of amniotic fluid protein composition

Amniotic fluid (AF), routinely used for prenatal diagnosis, contains large amounts of proteins produced by the amnion epithelial cells, fetal tissues, fetal excretions and placental tissuesAlthough many amniotic fluid proteins have been identified and are currently used to detect potential fetal ano...

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Bibliographische Detailangaben
Veröffentlicht in:Journal of prenatal medicine. - 2007. - 3(2009), 3 vom: 30. Juli, Seite 39-41
1. Verfasser: Perluigi, Marzia (VerfasserIn)
Weitere Verfasser: Di Domenico, Fabio, Cini, Chiara, Coccia, Raffaella, Giorlandino, Francesca Romana, Giorlandino, Maurizio, Cignini, Pietro, Mesoraca, Alvaro, Giorlandino, Claudio
Format: Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Journal of prenatal medicine
Schlagworte:Journal Article amniotic fluid protein proteomic analysis
Beschreibung
Zusammenfassung:Amniotic fluid (AF), routinely used for prenatal diagnosis, contains large amounts of proteins produced by the amnion epithelial cells, fetal tissues, fetal excretions and placental tissuesAlthough many amniotic fluid proteins have been identified and are currently used to detect potential fetal anomalies, little is known about the functions of these proteins and how they interact with one another. Identification of changes in the protein content of amniotic fluid, therefore, may be used to detect a particular type of pathology, or to ascertain a specific genetic disorder. In the present work we used a proteomic approach, combining 2DE and MS, in order to study the protein composition of AFS
Beschreibung:Date Completed 23.08.2012
Date Revised 21.10.2021
published: Print
Citation Status PubMed-not-MEDLINE
ISSN:1971-3282