Improvement in the quality of hematopoietic prostaglandin D synthase crystals in a microgravity environment
Human hematopoietic prostaglandin synthase, one of the better therapeutic target enzymes for allergy and inflammation, was crystallized with 22 inhibitors and in three inhibitor-free conditions in microgravity. Most of the space-grown crystals showed better X-ray diffraction patterns than the terres...
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| Veröffentlicht in: | Journal of synchrotron radiation. - 1994. - 18(2011), 1 vom: 28. Jan., Seite 88-91
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| 1. Verfasser: |
Tanaka, Hiroaki
(VerfasserIn) |
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| Weitere Verfasser: |
Tsurumura, Toshiharu,
Aritake, Kosuke,
Furubayashi, Naoki,
Takahashi, Sachiko,
Yamanaka, Mari,
Hirota, Erika,
Sano, Satoshi,
Sato, Masaru,
Kobayashi, Tomoyuki,
Tanaka, Tetsuo,
Inaka, Koji,
Urade, Yoshihiro |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2011
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| Zugriff auf das übergeordnete Werk: | Journal of synchrotron radiation
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine
Lipocalins
Piperidines
Intramolecular Oxidoreductases
EC 5.3.-
prostaglandin R2 D-isomerase
EC 5.3.99.2 |
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