Galectin-9 ameliorates immune complex-induced arthritis by regulating Fc gamma R expression on macrophages

Galectin-9 up-regulated Fc gamma RIIb expression of mouse peritoneal macrophages in vitro but down-regulated Fc gamma RIII expression. Galectin-9-treated macrophages stimulated with immune complexes (IC) produced less TNFalpha and IL-1 beta but more IL-10 than PBS-treated macrophages. Macrophage enh...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 133(2009), 3 vom: 09. Dez., Seite 382-92
1. Verfasser: Arikawa, Tomohiro (VerfasserIn)
Weitere Verfasser: Watanabe, Kota, Seki, Masako, Matsukawa, Akihiro, Oomizu, Souichi, Sakata, Ken-mei, Sakata, Atsuko, Ueno, Masaki, Saita, Naoki, Niki, Toshiro, Yamauchi, Akira, Hirashima, Mitsuomi
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antigen-Antibody Complex Cytokines Fc gamma receptor IIB Galectins RNA, Messenger Receptors, IgG galectin 9, mouse