Cultured peripheral blood mast cells from chronic idiopathic urticaria patients spontaneously degranulate upon IgE sensitization : Relationship to expression of Syk and SHIP-2
Recently, signaling changes in the FcvarepsilonRI pathway involving inositol lipid phosphatases have been identified in the basophils of chronic idiopathic urticaria (CIU) subjects. Based on the profile of basophil FcvarepsilonRI-mediated histamine degranulation, we have segregated CIU subjects into...
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Bibliographische Detailangaben
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 132(2009), 3 vom: 01. Sept., Seite 342-8
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| 1. Verfasser: |
Saini, Sarbjit S
(VerfasserIn) |
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| Weitere Verfasser: |
Paterniti, Miya,
Vasagar, Kavitha,
Gibbons, Scott P Jr,
Sterba, Patricia M,
Vonakis, Becky M |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2009
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
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| Schlagworte: | Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Antibodies
Intracellular Signaling Peptides and Proteins
Receptors, IgE
Immunoglobulin E
37341-29-0
Histamine
820484N8I3
mehr...
Protein-Tyrosine Kinases
EC 2.7.10.1
Proto-Oncogene Proteins c-kit
SYK protein, human
EC 2.7.10.2
Syk Kinase
Phosphoric Monoester Hydrolases
EC 3.1.3.2
Inositol Polyphosphate 5-Phosphatases
EC 3.1.3.56
INPP5D protein, human
EC 3.1.3.86
INPPL1 protein, human
Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases |
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