Combination of CTLA-4 and TGFbeta1 gene polymorphisms associated with dengue hemorrhagic fever and virus load in a dengue-2 outbreak
The pathogenesis of dengue hemorrhagic fever (DHF) has been considered to be massive immune activation of T cells. Abnormal expression of the immune regulatory molecules, CTLA-4 and TGFbeta1, leads to disturbances of regulatory T cell immune response. We investigate the contribution of CTLA-4 and TG...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 131(2009), 3 vom: 01. Juni, Seite 404-9
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1. Verfasser: |
Chen, Rong-Fu
(VerfasserIn) |
Weitere Verfasser: |
Wang, Lin,
Cheng, Jiin-Tsuey,
Chuang, Hau,
Chang, Jen-Chieh,
Liu, Jien-Wei,
Lin, I-Chun,
Yang, Kuender D |
Format: | Online-Aufsatz
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Sprache: | English |
Veröffentlicht: |
2009
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Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
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Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Antigens, CD
CTLA-4 Antigen
CTLA4 protein, human
Transforming Growth Factor beta1 |