Selective screening of secretory vesicle-associated proteins for autoantigens in type 1 diabetes : VAMP2 and NPY are new minor autoantigens
The four major autoantigens (IA-2, IA-2 beta, GAD65 and insulin) of type 1 diabetes are all associated with dense core or synaptic vesicles. This raised the possibility that other secretory vesicle-associated proteins might be targets of the autoimmune response in type 1 diabetes. To test this hypot...
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Détails bibliographiques
Publié dans: | Clinical immunology (Orlando, Fla.). - 1999. - 127(2008), 3 vom: 01. Juni, Seite 366-74
|
Auteur principal: |
Hirai, Hiroki
(Auteur) |
Autres auteurs: |
Miura, Junnosuke,
Hu, Yafang,
Larsson, Helena,
Larsson, Karin,
Lernmark, Ake,
Ivarsson, Sten-A,
Wu, Tianxia,
Kingman, Albert,
Tzioufas, Athanasios G,
Notkins, Abner L |
Format: | Article en ligne
|
Langue: | English |
Publié: |
2008
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Accès à la collection: | Clinical immunology (Orlando, Fla.)
|
Sujets: | Journal Article
Research Support, N.I.H., Intramural
Autoantibodies
Autoantigens
Neuropeptide Y
Vesicle-Associated Membrane Protein 2 |