Intrinsic ability of GM+IL-4 but not Flt3L-induced rat dendritic cells to promote allogeneic T cell hyporesponsiveness

Intrinsic ability of GM+IL-4 but not Flt3L-induced rat dendritic cells to promote allogeneic T cell hyporesponsiveness

The influence of GM+IL-4 and Flt3 ligand (FL) on phenotype and function of BM-derived DC from Lewis rats was investigated. GM+IL-4-induced DC, despite expression of CD80/CD86, were less stimulatory than FL-induced DC that expressed low CD80/CD86 and were efficient stimulators of allogeneic T cells....

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 123(2007), 2 vom: 20. Mai, Seite 176-89
1. Verfasser: Taieb, Aurele (VerfasserIn)
Weitere Verfasser: Breitinger, Jeremy J, Unadkat, Jignesh V, Shufesky, William J, Morelli, Adrian E, Thomson, Angus W, Lee, W P Andrew, Feili-Hariri, Maryam
Format: Aufsatz
Sprache:English
Veröffentlicht: 2007
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Antibodies, Monoclonal Antigens, CD Dinucleoside Phosphates Histocompatibility Antigens Isoantigens Lipopolysaccharides Membrane Proteins mehr... Receptors, Antigen, T-Cell flt3 ligand protein Interleukin-4 207137-56-2 cytidylyl-3'-5'-guanosine 2382-65-2 Granulocyte-Macrophage Colony-Stimulating Factor 83869-56-1 Interferons 9008-11-1