Monoclonal anti-double-stranded DNA antibodies cross-react with phosphoglycerate kinase 1 and inhibit the expression and production of IL-2 in activated Jurkat T cell line
Anti-double strand DNA antibodies (anti-dsDNA) involve in lupus nephritis. However, their role in tissue damage mechanism remains unclear. In this study, a 45-kDa cognate antigen of anti-dsDNA monoclonal antibodies 9D7 was identified by two-dimensional gel electrophoresis and determined to be human...
Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 120(2006), 3 vom: 28. Sept., Seite 326-34 |
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Weitere Verfasser: | , , , , |
Format: | Aufsatz |
Sprache: | English |
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2006
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Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.) |
Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Antibodies, Antinuclear Antibodies, Monoclonal Cytokines Interleukin-2 RNA, Messenger DNA 9007-49-2 Phosphoglycerate Kinase mehr... |