Structure determination of a sildenafil analogue contained in commercial herb drinks
Copyright 2004 John Wiley & Sons, Ltd.
| Publié dans: | Magnetic resonance in chemistry : MRC. - 1985. - 42(2004), 12 vom: 15. Dez., Seite 1060-2 |
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| Auteur principal: | |
| Autres auteurs: | , , |
| Format: | Article |
| Langue: | English |
| Publié: |
2004
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| Accès à la collection: | Magnetic resonance in chemistry : MRC |
| Sujets: | Journal Article Research Support, Non-U.S. Gov't Piperazines Purines Sulfones Sildenafil Citrate BW9B0ZE037 |
| Résumé: | Copyright 2004 John Wiley & Sons, Ltd. It was found from HPLC analysis that a commercial herb drink contains a putative sildenafil analog. In order to identify the sildenafil-like compound, separation and purification were carried out. The structure determination was performed based on routine 1D and 2D NMR experiments. Unlike sildenafil, the compound contains an ethylpiperazine instead of a methylpiperazine group. In addition, the piperazine and phenyl groups are connected through an acetyl group instead of the sulfonyl group of sildenafil |
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| Description: | Date Completed 18.04.2005 Date Revised 19.11.2015 published: Print Citation Status MEDLINE |
| ISSN: | 1097-458X |