Structure determination of a sildenafil analogue contained in commercial herb drinks

Copyright 2004 John Wiley & Sons, Ltd.

Bibliographische Detailangaben
Veröffentlicht in:Magnetic resonance in chemistry : MRC. - 1985. - 42(2004), 12 vom: 15. Dez., Seite 1060-2
1. Verfasser: Shin, Choonshik (VerfasserIn)
Weitere Verfasser: Hong, Mooki, Kim, Daibyung, Lim, Yoongho
Format: Aufsatz
Sprache:English
Veröffentlicht: 2004
Zugriff auf das übergeordnete Werk:Magnetic resonance in chemistry : MRC
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Piperazines Purines Sulfones Sildenafil Citrate BW9B0ZE037
Beschreibung
Zusammenfassung:Copyright 2004 John Wiley & Sons, Ltd.
It was found from HPLC analysis that a commercial herb drink contains a putative sildenafil analog. In order to identify the sildenafil-like compound, separation and purification were carried out. The structure determination was performed based on routine 1D and 2D NMR experiments. Unlike sildenafil, the compound contains an ethylpiperazine instead of a methylpiperazine group. In addition, the piperazine and phenyl groups are connected through an acetyl group instead of the sulfonyl group of sildenafil
Beschreibung:Date Completed 18.04.2005
Date Revised 19.11.2015
published: Print
Citation Status MEDLINE
ISSN:1097-458X