Structure determination of a sildenafil analogue contained in commercial herb drinks

Copyright 2004 John Wiley & Sons, Ltd.

Bibliographische Detailangaben
Veröffentlicht in:Magnetic resonance in chemistry : MRC. - 1985. - 42(2004), 12 vom: 15. Dez., Seite 1060-2
1. Verfasser: Shin, Choonshik (VerfasserIn)
Weitere Verfasser: Hong, Mooki, Kim, Daibyung, Lim, Yoongho
Format: Aufsatz
Sprache:English
Veröffentlicht: 2004
Zugriff auf das übergeordnete Werk:Magnetic resonance in chemistry : MRC
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Piperazines Purines Sulfones Sildenafil Citrate BW9B0ZE037
LEADER 01000naa a22002652 4500
001 NLM150606001
003 DE-627
005 20231223054216.0
007 tu
008 231223s2004 xx ||||| 00| ||eng c
028 5 2 |a pubmed24n0502.xml 
035 |a (DE-627)NLM150606001 
035 |a (NLM)15386550 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Shin, Choonshik  |e verfasserin  |4 aut 
245 1 0 |a Structure determination of a sildenafil analogue contained in commercial herb drinks 
264 1 |c 2004 
336 |a Text  |b txt  |2 rdacontent 
337 |a ohne Hilfsmittel zu benutzen  |b n  |2 rdamedia 
338 |a Band  |b nc  |2 rdacarrier 
500 |a Date Completed 18.04.2005 
500 |a Date Revised 19.11.2015 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a Copyright 2004 John Wiley & Sons, Ltd. 
520 |a It was found from HPLC analysis that a commercial herb drink contains a putative sildenafil analog. In order to identify the sildenafil-like compound, separation and purification were carried out. The structure determination was performed based on routine 1D and 2D NMR experiments. Unlike sildenafil, the compound contains an ethylpiperazine instead of a methylpiperazine group. In addition, the piperazine and phenyl groups are connected through an acetyl group instead of the sulfonyl group of sildenafil 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Piperazines  |2 NLM 
650 7 |a Purines  |2 NLM 
650 7 |a Sulfones  |2 NLM 
650 7 |a Sildenafil Citrate  |2 NLM 
650 7 |a BW9B0ZE037  |2 NLM 
700 1 |a Hong, Mooki  |e verfasserin  |4 aut 
700 1 |a Kim, Daibyung  |e verfasserin  |4 aut 
700 1 |a Lim, Yoongho  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Magnetic resonance in chemistry : MRC  |d 1985  |g 42(2004), 12 vom: 15. Dez., Seite 1060-2  |w (DE-627)NLM098179667  |x 1097-458X  |7 nnns 
773 1 8 |g volume:42  |g year:2004  |g number:12  |g day:15  |g month:12  |g pages:1060-2 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 42  |j 2004  |e 12  |b 15  |c 12  |h 1060-2