Differences in CCR5 expression on peripheral blood CD4+CD28- T-cells and in granulomatous lesions between localized and generalized Wegener's granulomatosis

Differences in CCR5 expression on peripheral blood CD4+CD28- T-cells and in granulomatous lesions between localized and generalized Wegener's granulomatosis

Wegener's granulomatosis (WG) is an autoimmune disease characterized by granulomatous lesions and a necrotizing vasculitis. Th1-type-cells lacking CD28 are expanded independent of age and immunosuppressive therapy in WG. To address their migratory properties of CD4(+)CD28(-) T-cells we studied...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 108(2003), 1 vom: 15. Juli, Seite 1-7
1. Verfasser: Lamprecht, Peter (VerfasserIn)
Weitere Verfasser: Bruhl, Hilke, Erdmann, Anika, Holl-Ulrich, Konstanze, Csernok, Elena, Seitzer, Ulrike, Mack, Matthias, Feller, Alfred C, Reinhold-Keller, Eva, Gross, Wolfgang L, Muller, Antje
Format: Aufsatz
Sprache:English
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Review CD28 Antigens Receptors, CCR5