Hierarchically Structured P-Doped MoS2/MoO2 Ultrathin Nanosheets on N-Doped Carbon Hemispheres for Sensitive Dopamine Detection
Dopamine (DA) is a key neurotransmitter in the central nervous system, and abnormal concentrations are associated with a variety of diseases. In this study, a novel electrochemical sensor is constructed based on ultrathin P-doped MoS2/MoO2 nanosheets supported on bowl-shaped N-doped carbon hemispher...
| Publié dans: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 41(2025), 31 vom: 12. Aug., Seite 20723-20733 |
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| Auteur principal: | |
| Autres auteurs: | , , , , |
| Format: | Article en ligne |
| Langue: | English |
| Publié: |
2025
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| Accès à la collection: | Langmuir : the ACS journal of surfaces and colloids |
| Sujets: | Journal Article Molybdenum 81AH48963U Dopamine VTD58H1Z2X Disulfides molybdenum disulfide ZC8B4P503V Carbon 7440-44-0 plus... |
| Résumé: | Dopamine (DA) is a key neurotransmitter in the central nervous system, and abnormal concentrations are associated with a variety of diseases. In this study, a novel electrochemical sensor is constructed based on ultrathin P-doped MoS2/MoO2 nanosheets supported on bowl-shaped N-doped carbon hemispheres (N-BCHP-MoS2/MoO2). The unique hierarchical structure combines the high specific surface area of N-BCH with the enhanced electrocatalytic activity of P-doped MoS2/MoO2, resulting in significant improvements in the performance for DA detection. The electronic structure of the catalyst is further modulated by the codoping of N and P, which increases the electrical conductivity and the number of active centers. The results show that the N-BCH@P-MoS2/MoO2 exhibits excellent sensitivity and selectivity for DA detection, capable of achieving a detection limit as low as 0.12 μM within a broad concentration range (3-100 μM) (S/N = 3). Furthermore, electrocatalysts have been employed in the detection of DA in human serum, indicating significant promise for clinical diagnosis |
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| Description: | Date Completed 12.08.2025 Date Revised 12.08.2025 published: Print-Electronic Citation Status MEDLINE |
| ISSN: | 1520-5827 |
| DOI: | 10.1021/acs.langmuir.5c02156 |