A Multifunctional DNA Nanoassembly for Cancer Cell Detection and Combined Gene-Chemotherapy Therapy
Although DNAzyme is a promising gene therapy agent, low cellular uptake efficiency, poor biological stability, and the unsatisfactory effect of monotherapy limit its development. Herein, a multifunctional DNA nanoassembly (RCA product-aptamer-DNAzyme, RAD) was constructed for cancer cell detection a...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 40(2024), 49 vom: 10. Dez., Seite 26033-26040
|
1. Verfasser: |
Zhang, Ruyan
(VerfasserIn) |
Weitere Verfasser: |
Zhou, Ting,
Huo, Xiaobing,
Du, Huan,
Ning, Gan,
Weng, Tianxin,
Wang, Xiufeng,
Zhang, Guodong,
Wang, Fang,
Zhang, Zhiqing |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2024
|
Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
|
Schlagworte: | Journal Article
Doxorubicin
80168379AG
DNA, Catalytic
Aptamers, Nucleotide |