A Multifunctional DNA Nanoassembly for Cancer Cell Detection and Combined Gene-Chemotherapy Therapy

Although DNAzyme is a promising gene therapy agent, low cellular uptake efficiency, poor biological stability, and the unsatisfactory effect of monotherapy limit its development. Herein, a multifunctional DNA nanoassembly (RCA product-aptamer-DNAzyme, RAD) was constructed for cancer cell detection a...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 40(2024), 49 vom: 10. Dez., Seite 26033-26040
1. Verfasser: Zhang, Ruyan (VerfasserIn)
Weitere Verfasser: Zhou, Ting, Huo, Xiaobing, Du, Huan, Ning, Gan, Weng, Tianxin, Wang, Xiufeng, Zhang, Guodong, Wang, Fang, Zhang, Zhiqing
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Doxorubicin 80168379AG DNA, Catalytic Aptamers, Nucleotide