Mixtures of Intrinsically Disordered Neuronal Protein Tau and Anionic Liposomes Reveal Distinct Anionic Liposome-Tau Complexes Coexisting with Tau Liquid-Liquid Phase-Separated Coacervates
Tau, an intrinsically disordered neuronal protein and polyampholyte with an overall positive charge, is a microtubule (MT) associated protein that binds to anionic domains of MTs and suppresses their dynamic instability. Aberrant tau-MT interactions are implicated in Alzheimer's and other neuro...
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| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1999. - 40(2024), 40 vom: 08. Okt., Seite 21041-21051
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| 1. Verfasser: |
Tchounwou, Christine
(VerfasserIn) |
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| Weitere Verfasser: |
Jobanputra, Anjali J,
Lasher, Dylan,
Fletcher, Bretton J,
Jacinto, Jorge,
Bhaduri, Arjun,
Best, Rebecca L,
Fisher, William S,
Ewert, Kai K,
Li, Youli,
Feinstein, Stuart C,
Safinya, Cyrus R |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2024
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
tau Proteins
Liposomes
Anions
Phosphatidylcholines
1,2-dioleoylphosphatidylserine
70614-14-1
Phosphatidylserines
1,2-oleoylphosphatidylcholine
EDS2L3ODLV
mehr...
Phosphatidylglycerols
1,2-dioleoyl-sn-glycero-3-phosphoglycerol
66322-31-4
Intrinsically Disordered Proteins |
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