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|a 10.1111/vcp.13377
|2 doi
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|a pubmed24n1548.xml
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|a (NLM)39294107
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Guerlin, Maud
|e verfasserin
|4 aut
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| 245 |
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|a Validation of the Sysmex XN-V hematology analyzer for feline specimens
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|c 2024
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 24.09.2024
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|a Date Revised 24.09.2024
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2024 The Author(s). Veterinary Clinical Pathology published by Wiley Periodicals LLC on behalf of American Society for Veterinary Clinical Pathology.
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|a BACKGROUND: The Sysmex XN-V is derived from the new Sysmex XN series of human hematology analyzers. The main changes from the previously validated XT-2000iV analyzer include an optic-fluorescent analysis for platelets and a nucleated red blood cell (NRBC) count
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|a OBJECTIVE: We aimed to validate the Sysmex XN-V for feline blood following the American College for Veterinary Clinical Pathology and International Council for Standardization in Hematology recommendations
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|a METHODS: Feline EDTA blood specimens were analyzed on the Sysmex XN-V to evaluate repeatability, linearity, comparison with the XT-2000iV analyzer and manual methods, stability, and to verify the previously established Sysmex XT-2000iV RIs
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|a RESULTS: Repeatability was excellent for most variables. Visually determined linearity was excellent or good for most variables except eosinophils and platelet variables. The correlation between the XN-V and XT-2000iV analyzers was good (≥0.82) for all variables except reticulocyte indices. Correlations between the Sysmex XN-V and manual differential counts were good to excellent for most variables, acceptable for neutrophils, and fair for monocytes and NRBC. The previously established Sysmex XT-2000iV RIs can be used to interpret results from the Sysmex XN-V analyzer for most variables except red cell distribution width and reticulocyte variables. The RI for platelet variables could not be evaluated because of platelet clumps. Changes in the Sysmex XN-V measurements after storage at 4 and 24°C were similar to those described for the Sysmex XT-2000iV analyzer
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|a CONCLUSIONS: The performance of the Sysmex XN-V analyzer was good and compared favorably with the Sysmex XT-2000iV analyzer
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|a Journal Article
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|a Validation Study
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|a blood
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|a cat
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|a comparison study
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| 650 |
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|a method validation
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| 650 |
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4 |
|a platelet clumping
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1 |
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|a Granat, Fanny
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Grebert, Margot
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Braun, Jean-Pierre
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Geffré, Anne
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Bourgès-Abella, Nathalie
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Trumel, Catherine
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Veterinary clinical pathology
|d 1975
|g 53(2024), 3 vom: 17. Sept., Seite 294-308
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|g volume:53
|g year:2024
|g number:3
|g day:17
|g month:09
|g pages:294-308
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| 856 |
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|u http://dx.doi.org/10.1111/vcp.13377
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