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240905s2024 xx |||||o 00| ||eng c |
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|a 10.1002/adma.202407409
|2 doi
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|a pubmed24n1593.xml
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|a (DE-627)NLM377225045
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|a (NLM)39235391
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|a DE-627
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|e rakwb
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|a eng
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| 100 |
1 |
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|a Yu, Zhiqun
|e verfasserin
|4 aut
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| 245 |
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|a Robust Chiral Metal-Organic Framework Coatings for Self-Activating and Sustainable Biofouling Mitigation
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|c 2024
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 07.11.2024
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|a Date Revised 07.11.2024
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2024 Wiley‐VCH GmbH.
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|a Surface coatings are designed to mitigate pervasive biofouling herald, a new era of surface protection in complex biological environments. However, existing strategies are plagued by persistent and recurrent biofilm attachment, despite the use of bactericidal agents. Herein, a chiral metal-organic framework (MOF)-based coating with conformal microstructures to enable a new anti-biofouling mode that involves spontaneous biofilm disassembly followed by bacterial eradication is developed. A facile and universal metal-polyphenol network (MPN) is designed to robustly anchor the MOF nanoarmor of biocidal Cu2+ ions and anti-biofilm d-amino acid ligands to a variety of substrates across different material categories and surface topologies. Incorporating a diverse array of chiral amino acids endows the resultant coatings with widespread signals for biofilm dispersal, facilitating copper-catalyzed chemodynamic reactions and inherent mechano-bactericidal activities. This synergistic mechanism yields unprecedented anti-biofouling efficacy elucidated by RNA-sequencing transcriptomics analysis, enhancing broad-spectrum antibacterial activities, preventing biofilm formation, and destroying mature biofilms. Additionally, the chelation-directed amorphous/crystalline coatings can activate photoluminescent properties to inhibit the settlement of microalgae biofilms. This study provides a distinctive perspective on chirality-enhanced antimicrobial behaviors and pioneers a rational pathway toward developing next-generation anti-biofouling coatings for diverse applications
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|a Journal Article
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|a d‐amino acid
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|a metal‐polyphenol network
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|a metal–organic framework
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|a robust nanostructures
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|a synergistic anti‐biofouling
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|a Metal-Organic Frameworks
|2 NLM
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|a Anti-Bacterial Agents
|2 NLM
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|a Copper
|2 NLM
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| 650 |
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|a 789U1901C5
|2 NLM
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| 700 |
1 |
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|a Li, Xiangyu
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wang, Zhengxing
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Fan, Yongqiang
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhao, Wenjie
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Li, Dianzhong
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Xu, Dake
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Gu, Tingyue
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wang, Fuhui
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 36(2024), 45 vom: 01. Nov., Seite e2407409
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|g volume:36
|g year:2024
|g number:45
|g day:01
|g month:11
|g pages:e2407409
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|u http://dx.doi.org/10.1002/adma.202407409
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