A standardized protocol for sample preparation for scanning electron microscopy to visualize extrachromosomal DNA
Extrachromosomal DNA (ecDNA) are circular DNA structures associated with cancer and drug resistance. One specific type, double minute (DM) chromosomes, has been studied since the 1960s using imaging techniques like cytogenetics and fluorescence microscopy. Specialized techniques such as atomic force...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | BioTechniques. - 1988. - 76(2024), 7 vom: 26., Seite 311-321
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| 1. Verfasser: |
A Madren, Jillann
(VerfasserIn) |
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| Weitere Verfasser: |
Chen, Jingting,
Dennis, William,
Ford, Christina,
K White, Kristen,
Brunk, Elizabeth |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2024
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| Zugriff auf das übergeordnete Werk: | BioTechniques
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| Schlagworte: | Journal Article
correlative light and electron microscopy
double minute chromosomes
extrachromosomal DNA
fluorescence microscopy
scanning electron microscopy
DNA, Circular
DNA
9007-49-2 |
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