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240714s2024 xx |||||o 00| ||eng c |
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|a 10.1002/adma.202406179
|2 doi
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|a pubmed24n1563.xml
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|a (NLM)39003621
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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|a Lee, Jin Woong
|e verfasserin
|4 aut
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|a Monolithic DNApatite
|b An Elastic Apatite with Sub-Nanometer Scale Organo-Inorganic Structures
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|c 2024
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Revised 10.10.2024
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a © 2024 Wiley‐VCH GmbH.
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|a Hydroxyapatite (HA) exhibits outstanding biocompatibility, bioactivity, osteoconductivity, and natural anti-inflammatory properties. Pure HA, ion-doped HA, and HA-polymer composites are investigated, but critical limitations such as brittleness remain; numerous efforts are being made to address them. Herein, the novel self-crystallization of a polymeric single-stranded deoxyribonucleic acid (ssDNA) without additional phosphate ions for synthesizing deoxyribonucleic apatite (DNApatite) is presented. The synthesized DNApatite, DNA1Ca2.2(PO4)1.3OH2.1, has a repetitive dual phase of inorganic HA crystals and amorphous organic ssDNA at the sub-nm scale, forming nanorods. Its mechanical properties, including toughness and elasticity, are significantly enhanced compared with those of HA nanorod, with a Young's modulus similar to that of natural bone
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|a Journal Article
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|a DNA
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|a DNApatite
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|a bone mimicking structure
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|a elastic apatite
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|a organo–inorganic structure
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|a sub‐nanometer nacre mimetic architecture
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|a Lee, Byoungsang
|e verfasserin
|4 aut
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|a Park, Cheol Hyun
|e verfasserin
|4 aut
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|a Heo, Jun Hyuk
|e verfasserin
|4 aut
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|a Lee, Tae Yoon
|e verfasserin
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|a Lee, Dongtak
|e verfasserin
|4 aut
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|a Bae, Jina
|e verfasserin
|4 aut
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|a Sundharbaabu, Priyannth Ramasami
|e verfasserin
|4 aut
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|a Yeom, Won Kyun
|e verfasserin
|4 aut
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|a Chae, Sudong
|e verfasserin
|4 aut
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|a Lim, Jae-Hyuk
|e verfasserin
|4 aut
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|a Lee, Seok-Won
|e verfasserin
|4 aut
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|a Choi, Jin-Seok
|e verfasserin
|4 aut
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|a Bae, Hyung-Bin
|e verfasserin
|4 aut
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|a Choi, Jae-Young
|e verfasserin
|4 aut
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|a Lee, Eun-Ho
|e verfasserin
|4 aut
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|a Yoon, Dae Sung
|e verfasserin
|4 aut
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|a Yeom, Geun Young
|e verfasserin
|4 aut
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|a Shin, Hyunjung
|e verfasserin
|4 aut
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| 700 |
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|a Lee, Jung Heon
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 36(2024), 41 vom: 07. Okt., Seite e2406179
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
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| 773 |
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|g volume:36
|g year:2024
|g number:41
|g day:07
|g month:10
|g pages:e2406179
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|u http://dx.doi.org/10.1002/adma.202406179
|3 Volltext
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