DeepMulticut : Deep Learning of Multicut Problem for Neuron Segmentation From Electron Microscopy Volume

Superpixel aggregation is a powerful tool for automated neuron segmentation from electron microscopy (EM) volume. However, existing graph partitioning methods for superpixel aggregation still involve two separate stages-model estimation and model solving, and therefore model error is inherent. To ad...

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Veröffentlicht in:IEEE transactions on pattern analysis and machine intelligence. - 1979. - 46(2024), 12 vom: 04. Nov., Seite 8696-8714
1. Verfasser: Li, Zhenchen (VerfasserIn)
Weitere Verfasser: Yang, Xu, Liu, Jiazheng, Hong, Bei, Zhang, Yanchao, Zhai, Hao, Shen, Lijun, Chen, Xi, Liu, Zhiyong, Han, Hua
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:IEEE transactions on pattern analysis and machine intelligence
Schlagworte:Journal Article
Beschreibung
Zusammenfassung:Superpixel aggregation is a powerful tool for automated neuron segmentation from electron microscopy (EM) volume. However, existing graph partitioning methods for superpixel aggregation still involve two separate stages-model estimation and model solving, and therefore model error is inherent. To address this issue, we integrate the two stages and propose an end-to-end aggregation framework based on deep learning of the minimum cost multicut problem called DeepMulticut. The core challenge lies in differentiating the NP-hard multicut problem, whose constraint number is exponential in the problem size. With this in mind, we resort to relaxing the combinatorial solver-the greedy additive edge contraction (GAEC)-to a continuous Soft-GAEC algorithm, whose limit is shown to be the vanilla GAEC. Such relaxation thus allows the DeepMulticut to integrate edge cost estimators, Edge-CNNs, into a differentiable multicut optimization system and allows a decision-oriented loss to feed decision quality back to the Edge-CNNs for adaptive discriminative feature learning. Hence, the model estimators, Edge-CNNs, can be trained to improve partitioning decisions directly while beyond the NP-hardness. Also, we explain the rationale behind the DeepMulticut framework from the perspective of bi-level optimization. Extensive experiments on three public EM datasets demonstrate the effectiveness of the proposed DeepMulticut
Beschreibung:Date Revised 08.11.2024
published: Print-Electronic
Citation Status PubMed-not-MEDLINE
ISSN:1939-3539
DOI:10.1109/TPAMI.2024.3409634