Disulfide/α-Amide-Bridged Doxorubicin Dimeric Prodrug : Effect of Aggregation Structures on pH/GSH Dual-Triggered Drug Release

Disulfide bonding has attracted intense interest in the tumor intracellular microenvironment-activated drug delivery systems (DDSs) in the last decades. Although various molecular structures of redox-responsive disulfide-containing DDSs have been developed, no investigation was reported on the effec...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 40(2024), 21 vom: 28. Mai, Seite 11098-11105
Auteur principal: Yang, Chen (Auteur)
Autres auteurs: Liu, Peng
Format: Article en ligne
Langue:English
Publié: 2024
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Prodrugs Doxorubicin 80168379AG Disulfides Glutathione GAN16C9B8O Amides Drug Carriers