Disulfide/α-Amide-Bridged Doxorubicin Dimeric Prodrug : Effect of Aggregation Structures on pH/GSH Dual-Triggered Drug Release

Disulfide bonding has attracted intense interest in the tumor intracellular microenvironment-activated drug delivery systems (DDSs) in the last decades. Although various molecular structures of redox-responsive disulfide-containing DDSs have been developed, no investigation was reported on the effec...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 40(2024), 21 vom: 28. Mai, Seite 11098-11105
1. Verfasser: Yang, Chen (VerfasserIn)
Weitere Verfasser: Liu, Peng
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Prodrugs Doxorubicin 80168379AG Disulfides Glutathione GAN16C9B8O Amides Drug Carriers