The prevalence and incidence of thrombotic primary antiphospholipid syndrome in adults aged 18-49 years : A population-based study in a mountain community in northern Italy

Copyright © 2023. Published by Elsevier Inc.

Détails bibliographiques
Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 260(2024) vom: 01. März, Seite 109905
Auteur principal: Andreoli, Laura (Auteur)
Autres auteurs: Nalli, Cecilia, Raffetti, Elena, Angeli, Fabrizio, Pascariello, Greta, Zentilin, Arianna, Pedersoli, Federica, Gasparotti, Cinzia, Magoni, Michele, Scarcella, Carmelo, Martini, Giuliana, Franceschini, Franco, Donato, Francesco, Tincani, Angela
Format: Article en ligne
Langue:English
Publié: 2024
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Antiphospholipid syndrome Incidence Myocardial infarction Prevalence Stroke Thrombosis
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245 1 4 |a The prevalence and incidence of thrombotic primary antiphospholipid syndrome in adults aged 18-49 years  |b A population-based study in a mountain community in northern Italy 
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520 |a OBJECTIVE: To estimate prevalence and incidence of thrombotic Primary Antiphospholipid Syndrome (PAPS) in the general population aged 18-49 years 
520 |a METHODS: The study was carried out in Valtrompia, a valley in northern Italy, in 2011-2015. The identification of PAPS cases leveraged three integrated sources: 1) Rheumatology Unit at the University Hospital; 2) General Practitioners; 3) hospital discharge codes of patients admitted for thrombotic events 
520 |a RESULTS: Prevalence and incidence were estimated as 22.9 (95% C.I. 11.4-41.0) and 5.0 (2.6-8.7) cases per 100,000 individuals, respectively. The estimates were 28.3 and 4.8, and 17.2 and 5.1 in males and females, respectively. The type of disease onset was mainly of arterial type in men and venous in women 
520 |a CONCLUSIONS: Thrombotic PAPS was found to be a rare disease in this population-based study. Prevalence and incidence were not significantly different between males and females aged 18-49 years, but a different type of onset was observed 
650 4 |a Journal Article 
650 4 |a Antiphospholipid syndrome 
650 4 |a Incidence 
650 4 |a Myocardial infarction 
650 4 |a Prevalence 
650 4 |a Stroke 
650 4 |a Thrombosis 
700 1 |a Nalli, Cecilia  |e verfasserin  |4 aut 
700 1 |a Raffetti, Elena  |e verfasserin  |4 aut 
700 1 |a Angeli, Fabrizio  |e verfasserin  |4 aut 
700 1 |a Pascariello, Greta  |e verfasserin  |4 aut 
700 1 |a Zentilin, Arianna  |e verfasserin  |4 aut 
700 1 |a Pedersoli, Federica  |e verfasserin  |4 aut 
700 1 |a Gasparotti, Cinzia  |e verfasserin  |4 aut 
700 1 |a Magoni, Michele  |e verfasserin  |4 aut 
700 1 |a Scarcella, Carmelo  |e verfasserin  |4 aut 
700 1 |a Martini, Giuliana  |e verfasserin  |4 aut 
700 1 |a Franceschini, Franco  |e verfasserin  |4 aut 
700 1 |a Donato, Francesco  |e verfasserin  |4 aut 
700 1 |a Tincani, Angela  |e verfasserin  |4 aut 
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