NIR-Emitting Gold Nanoclusters Encapsulated in PS-b-PEG Polymer Micelles

Gold nanoclusters (AuNCs) are an emerging type of luminescent probe, featuring good biocompatibility, high photostability, and large Stoke shifts. Their lack of colloidal stability is, however, a drawback for many applications. Here, we report the stabilization of AuNCs emitting in the NIR by a thio...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 40(2024), 3 vom: 23. Jan., Seite 1594-1603
1. Verfasser: Casteleiro, Bárbara (VerfasserIn)
Weitere Verfasser: de Francesco, Talita, Martinho, José Manuel Gaspar, Favier, Arnaud, Charreyre, Marie-Thérèse, Moffitt, Matthew G, Farinha, José Paulo Sequeira
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article
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520 |a Gold nanoclusters (AuNCs) are an emerging type of luminescent probe, featuring good biocompatibility, high photostability, and large Stoke shifts. Their lack of colloidal stability is, however, a drawback for many applications. Here, we report the stabilization of AuNCs emitting in the NIR by a thiol-terminated polystyrene chain (Mn = 5000 g mol-1). The optical properties of this nanocomposite remain invariant for 2 years in THF. To use the PS5k-AuNCs in an aqueous environment, these were encapsulated into polymer micelles using a polystyrene-b-poly(ethylene glycol) copolymer. The resulting hierarchical constructs, with diameters of ca. 125 to 215 nm, have promising properties for applications as luminescent probes such as contrast agents for biomedical imaging 
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700 1 |a de Francesco, Talita  |e verfasserin  |4 aut 
700 1 |a Martinho, José Manuel Gaspar  |e verfasserin  |4 aut 
700 1 |a Favier, Arnaud  |e verfasserin  |4 aut 
700 1 |a Charreyre, Marie-Thérèse  |e verfasserin  |4 aut 
700 1 |a Moffitt, Matthew G  |e verfasserin  |4 aut 
700 1 |a Farinha, José Paulo Sequeira  |e verfasserin  |4 aut 
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