NIR-Emitting Gold Nanoclusters Encapsulated in PS-b-PEG Polymer Micelles

Gold nanoclusters (AuNCs) are an emerging type of luminescent probe, featuring good biocompatibility, high photostability, and large Stoke shifts. Their lack of colloidal stability is, however, a drawback for many applications. Here, we report the stabilization of AuNCs emitting in the NIR by a thio...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 40(2024), 3 vom: 23. Jan., Seite 1594-1603
1. Verfasser: Casteleiro, Bárbara (VerfasserIn)
Weitere Verfasser: de Francesco, Talita, Martinho, José Manuel Gaspar, Favier, Arnaud, Charreyre, Marie-Thérèse, Moffitt, Matthew G, Farinha, José Paulo Sequeira
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article
Beschreibung
Zusammenfassung:Gold nanoclusters (AuNCs) are an emerging type of luminescent probe, featuring good biocompatibility, high photostability, and large Stoke shifts. Their lack of colloidal stability is, however, a drawback for many applications. Here, we report the stabilization of AuNCs emitting in the NIR by a thiol-terminated polystyrene chain (Mn = 5000 g mol-1). The optical properties of this nanocomposite remain invariant for 2 years in THF. To use the PS5k-AuNCs in an aqueous environment, these were encapsulated into polymer micelles using a polystyrene-b-poly(ethylene glycol) copolymer. The resulting hierarchical constructs, with diameters of ca. 125 to 215 nm, have promising properties for applications as luminescent probes such as contrast agents for biomedical imaging
Beschreibung:Date Revised 23.01.2024
published: Print-Electronic
Citation Status PubMed-not-MEDLINE
ISSN:1520-5827
DOI:10.1021/acs.langmuir.3c02104