Cryo-TEM Reveals the Influence of Multivalent Charge and PEGylation on Shape Transitions in Fluid Lipid Assemblies : From Vesicles to Discs, Rods, and Spheres

Lipids, and cationic lipids in particular are of interest as delivery vectors for hydrophobic drugs such as the cancer therapeutic paclitaxel, and the structures of lipid assemblies affect their efficacy. We investigated the effect of incorporating the multivalent cationic lipid MVL5 (+5e) and poly(...

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Publié dans:	Langmuir : the ACS journal of surfaces and colloids. - 1985. - 39(2023), 50 vom: 19. Dez., Seite 18424-18436
Auteur principal:	Steffes, Victoria M (Auteur)
Autres auteurs:	Zhang, Zhening, Ewert, Kai K, Safinya, Cyrus R
Format:	Article en ligne
Langue:	English
Publié:	2023
Accès à la collection:	Langmuir : the ACS journal of surfaces and colloids
Sujets:	Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural Micelles 1,2-dioleoyloxy-3-(trimethylammonium)propane MR86K0XRQP Phosphatidylcholines Fatty Acids, Monounsaturated Liposomes