Cryo-TEM Reveals the Influence of Multivalent Charge and PEGylation on Shape Transitions in Fluid Lipid Assemblies : From Vesicles to Discs, Rods, and Spheres

Lipids, and cationic lipids in particular are of interest as delivery vectors for hydrophobic drugs such as the cancer therapeutic paclitaxel, and the structures of lipid assemblies affect their efficacy. We investigated the effect of incorporating the multivalent cationic lipid MVL5 (+5e) and poly(...

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Veröffentlicht in:	Langmuir : the ACS journal of surfaces and colloids. - 1992. - 39(2023), 50 vom: 19. Dez., Seite 18424-18436
1. Verfasser:	Steffes, Victoria M (VerfasserIn)
Weitere Verfasser:	Zhang, Zhening, Ewert, Kai K, Safinya, Cyrus R
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2023
Zugriff auf das übergeordnete Werk:	Langmuir : the ACS journal of surfaces and colloids
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural Micelles 1,2-dioleoyloxy-3-(trimethylammonium)propane MR86K0XRQP Phosphatidylcholines Fatty Acids, Monounsaturated Liposomes