Preparation and Magnetic Manipulation of Fe3O4/Acrylic Resin Core-Shell Microspheres

Core-shell microspheres refer to duo-layer or multilayer microspheres, which are widely used in drug delivery, microreactors, etc. Accurate manipulation of microspheres is a research hot spot, while traditional manipulation methods including ultrasonic manipulation and laser manipulation still face...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 39(2023), 32 vom: 15. Aug., Seite 11459-11467
1. Verfasser: Zhou, Kejia (VerfasserIn)
Weitere Verfasser: Li, Junfu, Li, Wangming, Zhang, Yudong, Wang, Kuangbing, Xiong, Xinyi, Li, Shijiao, Chen, Xiaoyang, Cheng, Hsien-Wei, Qiu, Jingjiang, Wei, Ronghan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2023
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article
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520 |a Core-shell microspheres refer to duo-layer or multilayer microspheres, which are widely used in drug delivery, microreactors, etc. Accurate manipulation of microspheres is a research hot spot, while traditional manipulation methods including ultrasonic manipulation and laser manipulation still face some limitations. In this study, magnetic core-shell microspheres were adopted to realize the accurate manipulation of microspheres. Combined with microfluidic technology, polystyrene sulfonic acid (PSSA)/Fe3O4 magnetic fluid was utilized as the core material and photosensitive acrylic resin became the shell material. After UV curing, a magnetic core-shell microsphere with an average size of 55 μm could be achieved, and the diameter was uniform and controllable. By adjusting the flow rate of the dispersed phase, the dual-core microspheres with different core particle sizes that ranged from 9.3 to 28.4 μm could be prepared. Experimental results showed that the prepared Fe3O4/acrylic resin core-shell microspheres can be used as functionalized microspheres that have good magnetic response properties and self-assembly ability. In addition, the magnetic manipulation and self-assembly of the prepared core-shell microspheres were presented with different external magnetic fields. The magnetic core-shell microspheres have shown great potential in the fields of biomedical engineering and targeted delivery of drugs 
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700 1 |a Li, Junfu  |e verfasserin  |4 aut 
700 1 |a Li, Wangming  |e verfasserin  |4 aut 
700 1 |a Zhang, Yudong  |e verfasserin  |4 aut 
700 1 |a Wang, Kuangbing  |e verfasserin  |4 aut 
700 1 |a Xiong, Xinyi  |e verfasserin  |4 aut 
700 1 |a Li, Shijiao  |e verfasserin  |4 aut 
700 1 |a Chen, Xiaoyang  |e verfasserin  |4 aut 
700 1 |a Cheng, Hsien-Wei  |e verfasserin  |4 aut 
700 1 |a Qiu, Jingjiang  |e verfasserin  |4 aut 
700 1 |a Wei, Ronghan  |e verfasserin  |4 aut 
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