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231226s2023 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.3c01005
|2 doi
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|a pubmed24n1198.xml
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|a (DE-627)NLM359598250
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|a (NLM)37459162
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Chen, Ting
|e verfasserin
|4 aut
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| 245 |
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|a Smart Copolymer Surface Derived from Geminized Cationic Amphiphilic Polymers for Reversibly Switchable Bactericidal and Self-Cleaning Abilities
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|c 2023
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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| 500 |
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|a Date Completed 02.08.2023
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|a Date Revised 02.08.2023
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Bacterial adhesion and colonization on material surfaces pose a serious problem for healthcare-associated devices. Cationic amphiphilic polymer brushes are usually used as surface coatings in antibacterial materials to endow an interface with excellent bactericidal efficiency, but they are easily contaminated, which puts a great limitation on their application. Herein, novel antibacterial copolymer brush surfaces containing geminized cationic amphiphilic polymers (pAGC8) and thermoresponsive poly(N-isopropylacrylamide) polymers (pNIPAm) have been synthesized. Surface functionalization of polymer brushes was investigated by X-ray photoelectron spectroscopy, spectroscopic ellipsometry, atomic force microscopy, and water contact angle measurements. A proportion of AGC8 and NIPAm units in copolymer brushes has been adjusted to obtain a high-efficiency bactericidal surface with minimal interference to its self-cleaning property. The killing and releasing efficiency of the optimized surface simultaneously reached up to above 80% for both Staphylococcus aureus and Escherichia coli bacteria, and the bactericidal and self-cleaning abilities are still excellent even after three kill-release cycles. Such a novel copolymer brush system provides innovative guidance for the development of high-efficiency antibacterial materials in biomedical application
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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| 650 |
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|a Anti-Bacterial Agents
|2 NLM
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| 650 |
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|a Polymers
|2 NLM
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| 700 |
1 |
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|a Situ, Chaoyi
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Huang, Haohui
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Liang, Kuan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhao, Lianyu
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wang, Ziyuan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhao, Jishi
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Li, Yan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Duan, Chongxiong
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Sun, Haibo
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 39(2023), 30 vom: 01. Aug., Seite 10521-10529
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
1 |
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|g volume:39
|g year:2023
|g number:30
|g day:01
|g month:08
|g pages:10521-10529
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|u http://dx.doi.org/10.1021/acs.langmuir.3c01005
|3 Volltext
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|d 39
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|h 10521-10529
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