Self-Assembly of Peptide-Lipid Nanoparticles for the Efficient Delivery of Nucleic Acids

A transfection formulation is successfully developed to deliver nucleic acids by adding an auxiliary lipid (DOTAP) to the peptide, and the transfection efficiency of pDNA reaches 72.6%, which is close to Lipofectamine 2000. In addition, the designed KHL peptide-DOTAP complex exhibits good biocompati...

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Veröffentlicht in:	Langmuir : the ACS journal of surfaces and colloids. - 1985. - 39(2023), 21 vom: 30. Mai, Seite 7484-7494
1. Verfasser:	Zhang, Jiaojiao (VerfasserIn)
Weitere Verfasser:	Wang, Zixuan, Min, Jiwei, Zhang, Xuelin, Su, Rongxin, Wang, Yuefei, Qi, Wei
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2023
Zugriff auf das übergeordnete Werk:	Langmuir : the ACS journal of surfaces and colloids
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Lipid Nanoparticles Nucleic Acids 1,2-dioleoyloxy-3-(trimethylammonium)propane MR86K0XRQP Liposomes Peptides