Increasing the Capture Rate of Circulating Tumor DNA in Unaltered Plasma Using Passive Microfluidic Mixer Flow Cells

A limiting factor in using blood-based liquid biopsies for cancer detection is the volume of extracted blood required to capture a measurable number of circulating tumor DNA (ctDNA). To overcome this limitation, we developed a technology named the dCas9 capture system to capture ctDNA from unaltered...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1999. - 39(2023), 9 vom: 07. März, Seite 3225-3234
1. Verfasser: Downs, Bradley M (VerfasserIn)
Weitere Verfasser: Hoang, Tra-My, Cope, Leslie
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2023
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, U.S. Gov't, Non-P.H.S. Circulating Tumor DNA Proto-Oncogene Proteins B-raf EC 2.7.11.1 DNA 9007-49-2