Potential antimicrobial activity of camel milk as a traditional functional food against foodborne pathogens in vivo and in vitro

Foodborne pathogens are a leading cause of mortality worldwide. Therefore, strategies focused on functional foods are urgently required to tackle this issue. As a result, camel milk is one of the most important traditional functional foods since it contains a variety of bioactive components, which a...

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Veröffentlicht in:Food science and technology international = Ciencia y tecnologia de los alimentos internacional. - 1998. - 30(2024), 3 vom: 24. Apr., Seite 239-250
1. Verfasser: Abdelazez, Amro (VerfasserIn)
Weitere Verfasser: Melak, Sherif, Abdelmotaal, Heba, Alshehry, Garsa, Al-Jumayi, Huda, Algarni, Eman, Meng, Xiang-Chen
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Food science and technology international = Ciencia y tecnologia de los alimentos internacional
Schlagworte:Journal Article C57BL/6 mice Camel milk agar well diffusion technique antimicrobial activity foodborne pathogens (FBPs) Anti-Infective Agents
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520 |a Foodborne pathogens are a leading cause of mortality worldwide. Therefore, strategies focused on functional foods are urgently required to tackle this issue. As a result, camel milk is one of the most important traditional functional foods since it contains a variety of bioactive components, which all have antimicrobial activity against foodborne pathogens. The study aims to investigate the potential antimicrobial activity of raw camel milk against foodborne pathogens in both in vitro agar well diffusion and infected mice, especially Listeria monocytogenes, Staphylococcus aureus, Salmonella Typhimurium and Escherichia coli, particularly in societies that rely on consuming camel milk in its raw form. A total of eighty C57BL/6 mice were divided into ten groups and gavaged with or without camel milk for two consecutive weeks. A blood plasma analysis and serum insulin levels were measured. Histological investigations of the liver, pancreas, kidney, spleen, lung and testicles were also performed. In both in vivo and in vitro studies when compared to other pathogenic bacteria, E. coli was the most affected by raw camel milk, with a significant clear zone of 2.9 ± 0.13 cm in vitro and in all measured parameters in vivo (p < 0.05). As a result, we advocated for further research to improve camel breeding, raise milk yield and extend its reproductive capability as one of the most important farm animals 
650 4 |a Journal Article 
650 4 |a C57BL/6 mice 
650 4 |a Camel milk 
650 4 |a agar well diffusion technique 
650 4 |a antimicrobial activity 
650 4 |a foodborne pathogens (FBPs) 
650 7 |a Anti-Infective Agents  |2 NLM 
700 1 |a Melak, Sherif  |e verfasserin  |4 aut 
700 1 |a Abdelmotaal, Heba  |e verfasserin  |4 aut 
700 1 |a Alshehry, Garsa  |e verfasserin  |4 aut 
700 1 |a Al-Jumayi, Huda  |e verfasserin  |4 aut 
700 1 |a Algarni, Eman  |e verfasserin  |4 aut 
700 1 |a Meng, Xiang-Chen  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Food science and technology international = Ciencia y tecnologia de los alimentos internacional  |d 1998  |g 30(2024), 3 vom: 24. Apr., Seite 239-250  |w (DE-627)NLM098247832  |x 1532-1738  |7 nnas 
773 1 8 |g volume:30  |g year:2024  |g number:3  |g day:24  |g month:04  |g pages:239-250 
856 4 0 |u http://dx.doi.org/10.1177/10820132221146322  |3 Volltext 
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