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231226s2022 xx |||||o 00| ||eng c |
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|a 10.3928/23258160-20220919-01
|2 doi
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|a pubmed24n1158.xml
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|a (NLM)36239679
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|a DE-627
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|e rakwb
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|a eng
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| 100 |
1 |
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|a Lee, Sophie C
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Long-Term Retinal Vascular Changes in Age-Related Macular Degeneration Measured Using Optical Coherence Tomography Angiography
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|c 2022
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 18.10.2022
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|a Date Revised 22.12.2022
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a BACKGROUND AND OBJECTIVE: To determine if age-related macular degeneration (AMD) status affects longitudinal retinal vessel changes
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|a PATIENTS AND METHODS: Retrospective, cohort study of 125 eyes (75 patients) with AMD, following retinal vessel density (VD) and foveal avascular zone (FAZ) measurements using optical coherence tomography angiography (OCT-A) over 24 months
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| 520 |
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|a RESULTS: FAZ area (P < .001) and perimeter (P < .001) increased over 2 years, with no difference between nonexudative and exudative AMD (P = .134-.976). Eyes with geographic atrophy (GA) showed greater progressive VD loss (P = .023-.038), and greater increase in FAZ area (P = .044) and perimeter (P = .040) compared to eyes without GA. Neither baseline nor 2-year change in vascular parameters were associated with choroidal neovascularization (CNV) or GA incidence in nonexudative AMD, or anti-VEGF injection frequency in exudative AMD (P = .070-.952)
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|a CONCLUSION: AMD eyes with GA undergo more rapid loss of retinal vessel density and FAZ enlargement over 2 years, suggesting a relationship between the retinal vasculature and AMD pathophysiology. [Ophthalmic Surg Lasers Imaging Retina 2022;53:529-536.]
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|a Journal Article
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1 |
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|a Rusakevich, Alexander M
|e verfasserin
|4 aut
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1 |
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|a Amin, Aana
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Tran, Steven
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Emami-Naeini, Parisa
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Moshiri, Ala
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Park, Susanna S
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yiu, Glenn
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Ophthalmic surgery, lasers & imaging retina
|d 2013
|g 53(2022), 10 vom: 17. Okt., Seite 529-536
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|x 2325-8179
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|g volume:53
|g year:2022
|g number:10
|g day:17
|g month:10
|g pages:529-536
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