|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM342878697 |
| 003 |
DE-627 |
| 005 |
20231226015127.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231226s2022 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1111/nph.18348
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1142.xml
|
| 035 |
|
|
|a (DE-627)NLM342878697
|
| 035 |
|
|
|a (NLM)35766993
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Smythers, Amanda L
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Abscisic acid-controlled redox proteome of Arabidopsis and its regulation by heterotrimeric Gβ protein
|
| 264 |
|
1 |
|c 2022
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 28.09.2022
|
| 500 |
|
|
|a Date Revised 20.10.2022
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a © 2022 The Authors. New Phytologist © 2022 New Phytologist Foundation.
|
| 520 |
|
|
|a The plant hormone abscisic acid (ABA) plays crucial roles in regulation of stress responses and growth modulation. Heterotrimeric G-proteins are key mediators of ABA responses. Both ABA and G-proteins have also been implicated in intracellular redox regulation; however, the extent to which reversible protein oxidation manipulates ABA and/or G-protein signaling remains uncharacterized. To probe the role of reversible protein oxidation in plant stress response and its dependence on G-proteins, we determined the ABA-dependent reversible redoxome of wild-type and Gβ-protein null mutant agb1 of Arabidopsis. We quantified 6891 uniquely oxidized cysteine-containing peptides, 923 of which show significant changes in oxidation following ABA treatment. The majority of these changes required the presence of G-proteins. Divergent pathways including primary metabolism, reactive oxygen species response, translation and photosynthesis exhibited both ABA- and G-protein-dependent redox changes, many of which occurred on proteins not previously linked to them. We report the most comprehensive ABA-dependent plant redoxome and uncover a complex network of reversible oxidations that allow ABA and G-proteins to rapidly adjust cellular signaling to adapt to changing environments. Physiological validation of a subset of these observations suggests that functional G-proteins are required to maintain intracellular redox homeostasis and fully execute plant stress responses
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, U.S. Gov't, Non-P.H.S.
|
| 650 |
|
4 |
|a AGB1
|
| 650 |
|
4 |
|a Arabidopsis
|
| 650 |
|
4 |
|a G-protein
|
| 650 |
|
4 |
|a abscisic acid
|
| 650 |
|
4 |
|a photosynthesis
|
| 650 |
|
4 |
|a proteomics
|
| 650 |
|
4 |
|a redox
|
| 650 |
|
4 |
|a redox proteomics
|
| 650 |
|
7 |
|a AGB1 protein, Arabidopsis
|2 NLM
|
| 650 |
|
7 |
|a Arabidopsis Proteins
|2 NLM
|
| 650 |
|
7 |
|a GTP-Binding Protein beta Subunits
|2 NLM
|
| 650 |
|
7 |
|a Plant Growth Regulators
|2 NLM
|
| 650 |
|
7 |
|a Proteome
|2 NLM
|
| 650 |
|
7 |
|a Reactive Oxygen Species
|2 NLM
|
| 650 |
|
7 |
|a Abscisic Acid
|2 NLM
|
| 650 |
|
7 |
|a 72S9A8J5GW
|2 NLM
|
| 650 |
|
7 |
|a Heterotrimeric GTP-Binding Proteins
|2 NLM
|
| 650 |
|
7 |
|a EC 3.6.5.1
|2 NLM
|
| 650 |
|
7 |
|a Cysteine
|2 NLM
|
| 650 |
|
7 |
|a K848JZ4886
|2 NLM
|
| 700 |
1 |
|
|a Bhatnagar, Nikita
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Ha, Chien
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Majumdar, Parinita
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a McConnell, Evan W
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Mohanasundaram, Boominathan
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Hicks, Leslie M
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Pandey, Sona
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t The New phytologist
|d 1979
|g 236(2022), 2 vom: 06. Okt., Seite 447-463
|w (DE-627)NLM09818248X
|x 1469-8137
|7 nnns
|
| 773 |
1 |
8 |
|g volume:236
|g year:2022
|g number:2
|g day:06
|g month:10
|g pages:447-463
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1111/nph.18348
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 236
|j 2022
|e 2
|b 06
|c 10
|h 447-463
|