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231226s2022 xx |||||o 00| ||eng c |
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|a 10.1016/j.clim.2022.109031
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|a eng
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|a Tenbrock, Klaus
|e verfasserin
|4 aut
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|a T cell dysregulation in SLE
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|c 2022
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 02.06.2022
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|a Date Revised 24.07.2022
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Copyright © 2022. Published by Elsevier Inc.
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|a T helper cells aid B cells with the production of antibodies and thus play a central role in disease development of systemic lupus erythematosus (SLE). Numerous T helper cell abnormalities have been described in SLE patients that contribute to disease pathophysiology and provide suitable targets for therapeutic intervention. In addition, T effector cell also play a less well-defined role in SLE. This review focusses on underlying molecular mechanisms of different T cell alterations in SLE
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|a Journal Article
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|a Review
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|a CD4+ T cells
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|a CD8+ T cells
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|a Foxp3
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|a Lupus
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|a T follicular helper cells
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|a Tregs
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|a Rauen, Thomas
|e verfasserin
|4 aut
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|i Enthalten in
|t Clinical immunology (Orlando, Fla.)
|d 1999
|g 239(2022) vom: 15. Juni, Seite 109031
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|g volume:239
|g year:2022
|g day:15
|g month:06
|g pages:109031
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|u http://dx.doi.org/10.1016/j.clim.2022.109031
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