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231226s2022 xx |||||o 00| ||eng c |
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|a 10.1002/adma.202201989
|2 doi
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|a pubmed24n1127.xml
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|a (DE-627)NLM33837227X
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|a (NLM)35306702
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|a DE-627
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|a eng
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| 100 |
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|a Zhou, Cheng
|e verfasserin
|4 aut
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| 245 |
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|a Conjugated Oligoelectrolytes for Long-Term Tumor Tracking with Incremental NIR-II Emission
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|c 2022
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 23.05.2022
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|a Date Revised 23.05.2022
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2022 Wiley-VCH GmbH.
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|a The design and synthesis of the near-infrared (NIR)-II emissive conjugated oligoelectrolyte COE-BBT are reported. COE-BBT has a solubility in aqueous media greater than 50 mg mL-1 , low toxicity, and a propensity to intercalate lipid bilayers, wherein it exhibits a higher emission quantum yield relative to aqueous media. Addition of COE-BBT to cells provides two emission channels, at ≈500 and ≈1020 nm, depending on the excitation wavelength, which facilitates in vitro confocal microscopy and in vivo animal imaging. The NIR-II emission of COE-BBT is used to track intracranial and subcutaneous tumor progression in mice. Of relevance is that the total NIR-II intensity increases over time. This phenomenon is attributed to a progressive attenuation of a COE-BBT self-quenching effect within the cells due to the expected dye dilution per cell as the tumor proliferates
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|a Journal Article
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|a NIR-II window
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|a conjugated oligoelectrolytes
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|a fluorogenic materials
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|a tumor tracking
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|a Water
|2 NLM
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|a 059QF0KO0R
|2 NLM
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| 700 |
1 |
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|a Li, Zeshun
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhu, Ziyue
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Chia, Geraldine W N
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Mikhailovsky, Alexander
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Vázquez, Ricardo Javier
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Chan, Samuel J W
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Li, Kai
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Liu, Bin
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Bazan, Guillermo C
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 34(2022), 20 vom: 21. Mai, Seite e2201989
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
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| 773 |
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|g volume:34
|g year:2022
|g number:20
|g day:21
|g month:05
|g pages:e2201989
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|u http://dx.doi.org/10.1002/adma.202201989
|3 Volltext
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