Mechanistic Study of Membrane Disruption by Antimicrobial Methacrylate Random Copolymers by the Single Giant Vesicle Method

Cationic amphiphilic polymers have been a platform to create new antimicrobial materials that act by disrupting bacterial cell membranes. While activity characterization and chemical optimization have been done in numerous studies, there remains a gap in our knowledge on the antimicrobial mechanisms...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 37(2021), 33 vom: 24. Aug., Seite 9982-9995
1. Verfasser: Tsukamoto, Manami (VerfasserIn)
Weitere Verfasser: Zappala, Emanuele, Caputo, Gregory A, Kikuchi, Jun-Ichi, Najarian, Kayvan, Kuroda, Kenichi, Yasuhara, Kazuma
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Anti-Infective Agents Lipid Bilayers Methacrylates Phosphatidylcholines Polymers