Screening for androgen agonists using autonomously bioluminescent HEK293 reporter cells
Due to the public health concerns of endocrine-disrupting chemicals, there is an increasing demand to develop improved high-throughput detection assays for enhanced exposure control and risk assessment. A substrate-free, autobioluminescent HEK293ARE/Gal4-Lux assay was developed to screen compounds f...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | BioTechniques. - 1993. - 71(2021), 2 vom: 05. Aug., Seite 403-415
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| 1. Verfasser: |
Xu, Tingting
(VerfasserIn) |
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| Weitere Verfasser: |
Gilliam, Madison,
Sayler, Gary,
Ripp, Steven,
Close, Dan |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2021
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| Zugriff auf das übergeordnete Werk: | BioTechniques
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| Schlagworte: | Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
HEK293
androgen
autobioluminescence
bioreporter
endocrine disrupting chemical (EDC)
lux
Androgens |
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